Taste-masked pharmaceutical composition

Details Taste-masked pharmaceutical composition Taste-masked pharmaceutical composition

A - Human Necessities

61

K

A61K 47/32 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 9/68 (2006.01) A61K 31/426 (2006.01) A61K 45/08 (2006.01) A61P 1/00 (2006.01)

Patent

CA 2299423

A chewable dosage form containing a histamine H2-receptor antagonist in an amount which is effective to treat a gastrointestinal disorder is provided in a palatably acceptable form. The dosage form comprises granules containing the histamine H2--receptor antagonist, which are provided with a taste-masking coating comprising a water-insoluble, water-permeable methacrylate ester copolymer in which the coating is applied to the granules in an amount which provides a taste-masking effect for a relatively short period during which the composition is being chewed by a patient, but which allows substantially immediate release of the histamine H2-receptor antagonist after the composition has been chewed and ingested.

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