A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7048 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/365 (2006.01) A61K 31/7042 (2006.01) A61K 47/30 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2445606
The invention describes a composition suitable for oral administration comprising an antibiotic macrolide and a polycarbophil. The antibiotic macrolide is preferably clarithromycin. The polycarbophil is reported to have surprising taste-masking properties in combination with the antibiotic and acts by inhibiting the undesirable release of the antibiotic component in the mouth or stomach. Several methods of preparing granules of the antibiotic macrolide and polycarbophil are also described.
La présente invention concerne une composition pour administration par voie orale, renfermant un macrolide et un polycarbophile. Le macrolide est de préférence de la clarithromycine. Le polycarbophile permet de masquer efficacement le goût de certains médicaments lorsqu'il est combiné avec l'antibiotique et d'inhiber la libération indésirable du composant antibiotique dans la bouche ou dans l'estomac. L'invention concerne également plusieurs procédés destinés à la préparation de granules renfermant un macrolide et un polycarbophile.
Ferguson Phillip John
Hillier Charles
Macrae & Co.
Pacific Pharmaceuticals Limited
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