Tat signal peptides for producing proteins in prokaryotes

Details Tat signal peptides for producing proteins in prokaryotes Tat signal peptides for producing proteins in prokaryotes

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01) C12N 15/62 (2006.01) C12N 15/73 (2006.01) C12N 15/76 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2691109

This invention provides polynucleotides encoding TAT fusion proteins, and methods for producing proteins of interest in a host cell. In particular, the present invention relates to polynucleotides, vectors, polypeptides and methods for expressing organophosphate-degrading enzymes e.g. organophosphorus hydrolase (OPH) in host cell, such as a Streptomyces species host cell.

Cette invention porte sur des polynucléotides codants pour des protéines de fusion TAT et sur des procédés de fabrication de protéines d'intérêt dans une cellule hôte. En particulier, la présente invention porte sur des polynucléotides, des vecteurs, des polypeptides et des procédés pour exprimer des enzymes dégradant l'organophosphate, par exemple l'organophosphore hydrolase (OPH) dans une cellule hôte, telle qu'une cellule hôte de l'espèce Streptomyces.

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