Taxane-based compositions and methods of use

Details Taxane-based compositions and methods of use Taxane-based compositions and methods of use

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 31/28 (2006.01) A61K 31/335 (2006.01) A61K 31/355 (2006.01) A61K 38/13 (2006.01) A61K 47/02 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2404370

Disclosed are taxane-based compositions and methods of using the same to achieve target blood levels of a taxane in a mammal, e.g., to treat taxane- responsive malignant and non-malignant diseases. Compositions of the invention exhibit long-term stability and overall palatability. Also disclosed are methods for using the compositions as analytical tools for pharmacokinetic studies.

L'invention concerne des compositions à base de taxane et des procédés permettant d'utiliser ces compositions pour atteindre des concentrations sanguines cibles de taxane chez un mammifère, par exemple, pour traiter des maladies malignes et des maladies bénignes. Les compositions décrites dans cette invention présentent une stabilité à long terme et une sapidité globale. L'invention concerne également des procédés permettant d'utiliser ces compositions comme outils d'analyse dans des études pharmacocinétiques.

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