Taxane derivatives and processes for the preparation thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 493/08 (2006.01) A61K 31/335 (2006.01) A61K 31/357 (2006.01) C07D 263/06 (2006.01)

Patent

CA 2373530

A novel taxane derivative with anticancer activity, a process for its preparation and a process for the preparation of 14-.beta.-hydroxy-1,14- carbonate-baccatine III and V derivatives 13-substituted by an isoserine residue.

L'invention a trait à un nouveau dérivé de taxane possédant une activité anticancéreuse, à un procédé de préparation de celui-ci et à un procédé de préparation de dérivés de 14-.beta.-hydroxy-1,14-carbonate-baccatine III et V substitués en position 13 par un résidu isosérine.

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