C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 305/14 (2006.01)
Patent
CA 2498277
A general process for the functionalization at the 14- position of 13- ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula III, wherein the substituents are as defined in the disclosure, is also described.
Cette invention a trait à un procédé général de fonctionnalisation en position 14 de dérivés de 13-cétobaccatine et ce, afin d'obtenir des dérivés correspondant à la formule (II) dans laquelle les substituants sont tels que définis dans le descriptif. L'invention porte également sur la transformation des composés correspondant à la formule (II) en composés correspondant à la formule (III), les substituants étant tels que définis dans le descriptif.
Baldelli Eleonora
Battaglia Arturo
Bombardelli Ezio
Carenzi Giacomo
Fontana Gabriele
Indena S.p.a.
Kirby Eades Gale Baker
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