Taxane prodrugs

Details Taxane prodrugs Taxane prodrugs

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 31/282 (2006.01) A61K 31/704 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) A61K 47/30 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2440225

Taxane prodrugs comprise a taxane joined by a hydrolyzable bond to one or more oligomers that comprise a polyethylene glycol moiety. The oligomer preferably further comprises a salt-forming moiety.

L'invention concerne des promédicaments taxane contenant un taxane lié par une liaison hydrolysable à un ou plusieurs oligomère(s) comportant un groupe fonctionnel glycol polyéthylène. Cet oligomère comprend de préférence un groupe fonctionnel de formation de sel.

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