Taxanes having an amino substituted side-chain

Details Taxanes having an amino substituted side-chain Taxanes having an amino substituted side-chain

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) A61K 31/33 (2006.01) C07C 227/22 (2006.01) C07C 231/12 (2006.01) C07C 233/87 (2006.01) C07D 205/08 (2006.01) C07D 405/12 (2006.01) C07D 407/00 (2006.01) C07D 407/12 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07D 413/14 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2158275

Taxanes having side-chain substituted by a group CONX8X10 wherein X8 is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterosubstituted alkyl, alkenyl, alkynyl, aryl, heteroaryl, and X10 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterosubstituted alkyl, alkenyl, alkynyl, aryl, heteroaryl. The taxanes are useful anti-cancer and anti-leukemia agents.

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