C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) C12N 9/12 (2006.01) C12N 9/90 (2006.01) C12N 15/80 (2006.01) C12P 17/02 (2006.01)
Patent
CA 2336122
This invention relates to compositions and methods useful for producing extrachromosomal DNA, wherein such extrachromosomal DNA codes for a product which changes the level of taxol production. More specifically, the present invention relates to such compositions and methods for producing extrachromosomal DNA based on the unexpected discovery that the Pestalotiopsis fungi add one or more telomeric repeats to the ends of exogenous DNA.
L'invention concerne des compositions et des procédés utiles pour la constitution d'ADN extrachromosomique, ledit ADN codant un produit qui modifie le niveau de la production de taxol. Plus précisément, l'invention concerne des compositions et des procédés qui permettent de constituer de l'ADN extrachromosomique en utilisant la découverte inattendue selon laquelle les champignons Pestalotiopsis ajoutent une ou plusieurs répétitions télomériques aux extrémités de l'ADN exogène.
Long David M.
Smidansky Eric D.
Strobel Gary A.
Gowling Lafleur Henderson Llp
Montana State University - Bozeman
Research And Development Institute Inc.
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