Tbp2 fragments of the transferrine receptor of neisseria...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/22 (2006.01) A61K 39/095 (2006.01) A61K 39/40 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2167936

Polypeptide having a sequence of amino acids derived from that of the Tbp2 subunit of the transferrine receptor of a Neisseria meningitidis strain of the IM2169 or IM2394 type, the first, second and third domains being defined by maximum homologous alignment on the Tbp2 subunit sequence of the respective IM2169 or IM2394 reference strain, especially by total or partial deletion of at least one domain of said Tbp2 subunit of the IM2169 or IM2394 type provided the first and second domains are not fully deleted at the same time.

L'invention a pour objet un polypeptide ayant une séquence d'acides aminés qui dérive de celle de la sous-unité Tbp2 du récepteur transferrine d'une souche de Neisseria meningitidis de type IM2169 ou IM2394 dont les premier, deuxième et troisième domaines sont définis par alignement au maximum d'homologie, sur la séquence de la sous-unité Tbp2 de la souche de référence respective, IM2169 ou IM2394, notamment par délétion totale ou partielle d'au moins un domaine de ladite sous-unité Tbp2 de type IM2169 ou IM2394, à condition que le premier et le deuxième domaine ne soient pas simultanément et totalement délétés.

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