C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2629314
Disclosed are compounds of formula (I), wherein Q, R1, R2, R3, R4 and R5 are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
La présente invention concerne des composés de formule (I), dans laquelle Q, R1, R2, R3, R4 et R5 sont tels que définis ici. Les composés de l'invention inhibent la kinase Itk et ils peuvent donc être utilisés pour traiter des maladies et des états pathologiques impliquant une inflammation, des troubles immunologiques et des troubles allergiques. L'invention concerne également des procédés de préparation de ces composés et des compositions pharmaceutiques comprenant ces composés.
Bentzien Joerg Martin
Takahashi Hidenori
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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