Technetium-99m labeled peptides for imaging

Details Technetium-99m labeled peptides for imaging Technetium-99m labeled peptides for imaging

A - Human Necessities

61

K

A61K 51/08 (2006.01)

Patent

CA 2191950

This invention relates to radiolabeted peptides and methods for producing such peptides. Specifically, the invention relates to peptides, methods and kits for making such peptides, and methods for using such peptides to image sites in a mammalian body labeled with technetium-99m (Tc-99m) via a rediolabel-binding moiety covalently attached to a specific binding peptide via an amino acid side-chain of the peptide.

Cette invention se rapporte à des peptides radiomarqués et à leurs procédés de production. Spécifiquement, l'invention se rapporte à des peptides, à leurs procédés et à leurs matériels de fabrication, et à des procédés d'utilisation de ces peptides sur des sites d'imagerie dans le corps d'un mammifère marqué au technétium-99m (tc-99m) par l'intermédiaire d'une fraction de liaison de radiomarque fixée de manière covalente à un peptide spécifique de liaison par l'intermédiaire d'une chaîne latérale d'acides aminés du peptide.

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