Technetium-sulphonamide complexes, their use, pharmaceutical...

Details Technetium-sulphonamide complexes, their use, pharmaceutical... Technetium-sulphonamide complexes, their use, pharmaceutical...

C - Chemistry, Metallurgy

07

F

C07F 13/00 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) C07C 323/58 (2006.01) C07C 323/60 (2006.01) C07C 327/32 (2006.01) C07C 331/28 (2006.01) C07D 317/60 (2006.01) C07H 21/00 (2006.01) C07J 9/00 (2006.01) C07J 31/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2194561

The invention relates to novel chelate formers containing sulphonamide groups and their metallic chelates of general formula (I) in which n, m, p, V1, V2, V3, V4, X1, X2, X3, R1, R2, R3 and R4 have different meanings, pharmaceutical agents containing these compounds, their use in X-ray diagnosis and therapy, processes for producing these compounds and agents, and conjugates of these compounds with substances which selectively concentrate themselves in diseased tissue, especially peptides.

L'invention concerne de nouveaux chélateurs contenant des groupes sulfamides et leurs chélates métalliques de la formule générale (I) dans laquelle n, m, p, V?1¿, V?2¿, V?3¿, V?4¿, X?1¿, X?2¿, X?3¿, R?1¿, R?2¿, R?3¿ et R?4¿ ont diverses notations. L'invention concerne également des agents pharmaceutiques qui contiennent ces composés, leur utilisation en radiodiagnostic et en thérapie, des procédés permettant de préparer ces composés et ces agents, ainsi que des conjugués de ces composés avec des substances qui se concentrent de manière sélective dans des tissus malades, notamment des peptides.

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