Techniques for synthesis integrity evaluation utilizing...

C - Chemistry – Metallurgy – 40 – B

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C40B 40/04 (2006.01) C12Q 1/68 (2006.01) G06F 19/00 (2006.01) C07H 21/00 (2006.01) C40B 20/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2269846

Techniques for designing polymer probes to verify the integrity of the probe synthesis are provided. Multiple probes with identical sequences are designed so that the probes will be formed utilizing at least one different monomer addition cycle. Based on the probes affinity to a control target, variations (e.g., errors) in probe synthesis may be identified.

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