Telomerase interference

Details Telomerase interference Telomerase interference

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2466732

The invention relates to nucleic acids encoding or comprising interfering RNAs which target telomerase RNA or mRNA encoding the telomerase reverse transcriptase (TERT). The invention includes methods for inhibiting telomerase activity expression vectors, and pharmaceutical compositions.

Cette invention concerne des acides nucléiques codant ou comprenant des ARN d'interférence qui ciblent l'ARN télomérase ou un ARNm codant la transcriptase inverse de la télomérase (TERT). Cette invention concerne également des procédés d'inhibition de vecteurs d'expression de l'activité de la télomérase ainsi que des compositions pharmaceutiques.

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