C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2478681
The invention relates to nucleic acids encoding or comprising interfering RNAs which target telomerase RNA or mRNA encoding the telomerase reverse transcriptase (TERT). The invention includes methods for inhibiting telomerase activity expression vectors, and pharmaceutical compositions.
L'invention concerne des acides nucléiques codant ou comprenant des ARNs à effet interférant, qui ciblent l'ARN télomérase ou l'ARNm télomérase codant la transcriptase inverse de la télomérase (TERT). L'invention comprend également des procédés permettant d'inhiber les vecteurs d'expression de l'activité de la télomérase, ainsi que des compositions pharmaceutiques.
Rowley Peter T.
Smart & Biggar
University Of Rochester
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