Temperature-sensitive and cold-adapted human parainfluenza...

Details Temperature-sensitive and cold-adapted human parainfluenza... Temperature-sensitive and cold-adapted human parainfluenza...

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01) A61K 39/155 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 7/08 (2006.01)

Patent

CA 2336574

The present invention relates to isolated, attenuated viral strains of human parainfluenza virus 2 (HPIV-2), which are useful in live vaccine preparations. These strains exhibit a temperature sensitive and cold adapted phenotype useful for stimulating a protective immune response in an inoculated mammal without producing severe symptoms.

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