C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 39/155 (2006.01) C12N 7/08 (2006.01)
Patent
CA 2336961
The present invention relates to isolated, attenuated viral strains of human parainfluenza virus 2 (HPIV-2), which are useful in live vaccine preparations. These strains exhibit a temperature sensitive and cold adapted phenotype useful for stimulating a protective immune response in an inoculated mammal without producing severe symptoms.
La présente invention concerne des souches virales isolées, atténuées, du virus parainfluenza 2 humain (HPIV-2) qui sont utiles pour la préparation de vaccins. Ces souches présentent un phénotype thermosensible, adapté au froid, utile pour la stimulation d'une réponse immunitaire protectrice chez un mammifère inoculé sans apparition de symptômes graves.
Belshe Robert B.
Newman Frances K.
Smart & Biggar
St. Louis University
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