A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/34 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 38/00 (2006.01) A61K 38/28 (2006.01) A61K 38/44 (2006.01) A61K 38/48 (2006.01) A61K 47/10 (2006.01)
Patent
CA 2260967
Pharmaceutical compositions for the delivery of pharmacologically active proteins are provided by the present invention. The compositions of the present invention comprise a polymeric matrix having thermal gelation properties in which is incorporated a discrete suspension of at least one biologically active macromolecular polypeptide which retains greater than 90 percent of its biological activity. Furthermore, the concentration of the macromolecular polypeptide is greater than 0.5 percent by weight of the composition.
Compositions pharmaceutiques destinées à l'apport de protéines actives sur le plan pharmacologique. Les compositions selon la présente invention comprennent une matrice polymère présentant des propriétés de gélification thermique dans laquelle est incorporée une suspension discrète d'au moins un polypeptide macromoléculaire à activité biologique qui retient plus de 90 % de son activité biologique. En outre, la concentration du polypeptide macromoléculaire est supérieure à 0,5 % en poids de la composition.
Carpenter John F.
Manning Mark C.
Stratton Lewis P.
Carpenter John F.
Manning Mark C.
Smart & Biggar
Stratton Lewis P.
University Technology Corporation
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