Temporarily stiffened mesh prostheses

Details Temporarily stiffened mesh prostheses Temporarily stiffened mesh prostheses

A - Human Necessities

61

L

A61L 27/28 (2006.01) A61F 2/00 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) A61F 2/02 (2006.01)

Patent

CA 2637578

The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post--operative complications associated with their implantation, insertion or surgical use. By including biologically active agents and/or drugs in the coating, the devices provide prophylaxis for and can alleviate side effects or complications associated with the surgery or use of prostheses in general.

L'invention concerne des prothèses médicales et des procédés pour la fabrication de ces dispositifs. L'invention est caractérisée en ce que les prothèses sont des treillis temporairement raidis munis de revêtements particuliers fournissant une raideur initiale et facilitant ainsi la manipulation chirurgicale lors du traitement ou de la reconstruction de défauts des tissus mous. Des modes de réalisation préférés comprennent des treillis chirurgicaux revêtus d'un ou de plusieurs polymères biodégradables qui peuvent agir comme agent raidisseur en enrobant les filaments ou fibres du treillis afin d'immobiliser temporairement les points de contact de ces filaments ou fibres et/ou en augmentant la raideur du treillis d'au moins 1,1 fois sa rigidité initiale. Les dispositifs selon l'invention peuvent également éviter diverses complications post-opératoires associées à leur implantation, insertion ou utilisation chirurgicale. Grâce à l'inclusion d'agents biologiquement actifs et/ou de médicaments dans le revêtement, les dispositifs peuvent prévenir et soulager les effets secondaires ou complications associés à la chirurgie ou l'utilisation de prothèses en général.

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