Tenascin-w compositions and uses thereof

Details Tenascin-w compositions and uses thereof Tenascin-w compositions and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 35/04 (2006.01) C07K 14/47 (2006.01) C07K 14/78 (2006.01) C07K 16/18 (2006.01) C12Q 1/02 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2480050

Tenascin-W, an extracellular matrix molecule that is specificly expressed in metastatic tumours is provided. A system comprising a sample expressing tenascin-W is used as an in vitro method for screening possible anti-tumour agents or for agents that promote osteogenesis.

L'invention concerne la tenascine-W, une molécule de la matrice extracellulaire exprimée spécifiquement dans des tumeurs métastatiques. L'invention a également trait à l'utilisation d'un système contenant un échantillon exprimant la tenascine-W, ainsi qu'à un procédé in vitro de criblage d'éventuels agents anticancéreux et d'agents favorisant l'ostéogenèse.

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