Terephthalamate compounds and compositions, and their use as...

Details Terephthalamate compounds and compositions, and their use as... Terephthalamate compounds and compositions, and their use as...

C - Chemistry, Metallurgy

07

C

C07C 235/60 (2006.01) A61K 31/166 (2006.01) A61K 31/192 (2006.01) A61K 31/44 (2006.01) A61K 31/536 (2006.01) A61K 31/551 (2006.01) A61P 31/18 (2006.01) C07C 57/38 (2006.01) C07D 213/40 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 265/26 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2650329

Described herein are compounds having a terephthalamate structural feature. Also described herein, are methods of making such compounds, methods of using such compounds to modulate the activity of HIV integrase, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology of AIDS or infection with HIV.

L'invention concerne des composés ayant une caractéristique structurale de téréphtalamate. L'invention concerne également des procédés de fabrication de tels composés, des procédés d'utilisation de tels composés pour moduler l'activité de l'intégrase du VIH, et des compositions pharmaceutiques et des médicaments comprenant de tels composés. L'invention concerne également des procédés d'utilisation de tels composés, des compositions pharmaceutiques et des médicaments pour traiter et/ou prévenir et/ou inhiber et/ou améliorer la pathologie et/ou la symptomatologie du SIDA ou d'une infection par le VIH.

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