Terminal carboxy or tetrazole groups containing dialkyl ethers

Details Terminal carboxy or tetrazole groups containing dialkyl ethers Terminal carboxy or tetrazole groups containing dialkyl ethers

C - Chemistry, Metallurgy

07

C

C07C 69/708 (2006.01) A61K 31/11 (2006.01) A61K 31/19 (2006.01) A61K 31/21 (2006.01) A61K 31/41 (2006.01) C07C 47/198 (2006.01) C07C 47/277 (2006.01) C07C 47/37 (2006.01) C07C 59/305 (2006.01) C07C 59/315 (2006.01) C07C 59/325 (2006.01) C07C 59/353 (2006.01) C07C 59/64 (2006.01) C07C 69/716 (2006.01) C07C 69/734 (2006.01) C07D 257/04 (2006.01)

Patent

CA 2215233

Dialkyl ethers having terminal carboxy or tetrazole groups lower Lp(a) and triglycerides, and elevate HDL-cholesterol, and are thereby useful for treating vascular diseases and noninsulin-dependent diabetes mellitus.

La présente invention concerne des dialkyle éthers portant des groupes terminaux carboxy ou tétrazole qui abaissent le taux de lipoprotéines a (Lp(a)) et de triglycérides et élèvent le taux de cholestérol à lipoprotéines haute densité (HDL). Ces dialkyle éthers conviennent donc avantageusement au traitement des affections vasculaires ainsi que du diabète sucré non insulinodépendant.

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