C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 50/14 (2006.01) C07C 39/225 (2006.01) C07C 43/188 (2006.01) C07C 45/69 (2006.01) C07C 46/00 (2006.01) C07C 49/653 (2006.01) C07C 50/32 (2006.01) C07C 61/35 (2006.01) C07C 69/017 (2006.01) C07C 69/757 (2006.01) C07C 217/94 (2006.01) C07C 225/30 (2006.01) C07D 303/16 (2006.01)
Patent
CA 2173157
Terpene-quinone with antitumor activity defined from a cyclocondensation reaction of Diels-Alder, used to obtain families or series of said compounds having a new structure and presenting a cytotoxic activity to cellular cultures P-388, A-549, HT-29 and MEL-28, with levels of IC50 lower than 1 microgram per unit of millilitre.
Terpène-quinone avec activité antitumorale, définies à partir d'une réaction de cyclocondensation de Diels-Alder, permettant d'obtenir des familles ou séries de composés ayant une nouvelle structure et présentant une activité cytotoxique sur les cultures cellulaires P-388, A-549, HT-29 et MEL-28, atteignant des niveaux de IC¿50? inférieurs à 1 microgramme par unité de millilitre.
Garcia Gravalos Maria Dolores
Gordaliza Escobar Marina
Mahiques Bujanda Maria Del Mar
Miguel Del Corral Santana Jose Maria
San Feliciano Martin Arturo
Mbm Intellectual Property Law Llp
Pharma Mar S.a.
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