Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridine-3-yl)-amine...

Details Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridine-3-yl)-amine... Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridine-3-yl)-amine...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61P 25/00 (2006.01) A61P 43/00 (2006.01) C07D 487/04 (2006.01) C07D 513/04 (2006.01) C07F 9/6561 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2386804

The invention relates to tert.-butyl-(7-methyl-imidazo[1,2-a]pyridine-3-yl)- amine derivatives of the general structure (I), to a method for the preparation thereof and to medicaments that contain said compounds. The invention further relates to the use of the inventive tert.-butyl-(7-methyl- imidazo[1,2-a]pyridine-3-yl)-amine derivatives in the production of a medicament for the inhibition of the NO synthase and for the treatment of inter alia migraine and to pharmaceutical compositions that containtert.-butyl- (7-methyl-imidazo[1,2-a]pyridine-3-yl)-amine derivatives.

L'invention concerne des dérivés de tert.-butyl-(7-méthyl-imidazo[1,2-a]pyridine-3-yl)amine de la formule générale (I), ainsi qu'un procédé permettant de les préparer. L'invention concerne en outre des médicaments contenant lesdits composés, l'utilisation des dérivés de tert.-butyl-(7-méthyl-imidazo[1,2-a]pyridine-3-yl)amine obtenus selon l'invention pour produire un médicament visant à inhiber la synthase de NO et s'utilisant pour traiter entre autres la migraine, ainsi que des compositions pharmaceutiques contenant des dérivés de tert.-butyl-(7-méthyl-imidazo[1,2-a]pyridine-3-yl)amine.

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