Test for esterase activity in a liquid sample

C - Chemistry – Metallurgy – 12 – Q

Patent

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150/15, 150/3.2

C12Q 1/44 (2006.01)

Patent

CA 1179927

ABSTRACT OF THE DISCLOSURE A composition, test device and method for determining the presence of leukocytes, esterase and/or esterase activity in a test sample is dis- closed. The composition comprises an ester which, when cleaved by esterolytic activity, produces a detectable response such as color formation. In addition the composition comprises the compound 3- quinuclidinol. The device is prepared by incor- porating a carrier matrix, such as paper, with the composition. The method comprises contacting a test sample with the device and observing a detect able response.

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