Test methods and devices

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/26 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01) C07K 14/59 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2342683

A method and test device for differentiating between states of an analyte that can exist in different forms, such as follicle stimulating hormone (FSH). The method or test device uses a pair of specific binding agents, especially monoclonal antibodies, in two assays for the same analyte. The assays, applied to contemporaneous samples, differ from one another in format, one being a two step assay and the other being one step. A novel pair of anti-FSH monoclonal antibodies that can be used together in two such assays to differentiate pre- menopausal and post-menopausal FSH samples is disclosed.

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