C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/15 (2006.01) A61K 38/00 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01)
Patent
CA 2364669
The present invention relates to cystatin T (also known as zcys3) polypeptides and polynucleotides encoding the same. Cystatin T polypeptide is testis specific and homologous to cystatin-related epididymal specific gene (CRES) and type 2 cystatins. The polypeptides would be useful for modulating spermatogenesis and may be used to study or modulate that function in in vitro or in vivo systems. The present invention also includes antibodies to the cystatin T polypeptides.
L'invention concerne des polypeptides cystatine T (dits zcys3) et des polynucléotides les codant. Les polypeptides cystatine T sont spécifiques aux testicules et homologues au gène spécifique épididymaire se rapportant à la cystatine (CRES) et aux cystatines type 2. Les polypeptides seraient utiles pour moduler la spermatogénèse et peuvent servir à étudier ou à moduler cette fonction dans des systèmes in vitro et in vivo. Selon l'invention, des anticorps sont également incorporés aux polypeptides cystatine T.
Feldhaus Andrew L.
Holloway James L.
Feldhaus Andrew L.
Holloway James L.
Ledgley Law
Zymogenetics Inc.
LandOfFree
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