Testis-specific transcription factor zgcl-1

Details Testis-specific transcription factor zgcl-1 Testis-specific transcription factor zgcl-1

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2301043

Novel ZGCL-1 transcription factor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides, agonists and antagonists may be used within methods for promoting the proliferation and/or differentiation of testis cells, and may also be used in the development of male-specific contraceptives and infertility treatments.

L'invention concerne les polypeptides du nouveau facteur de transcription ZGCL-1, les polynucléotides codant les polypeptides ainsi que les compositions et méthodes associées. Les polypeptides, les agonistes et les antagonistes peuvent être utilisés dans des méthodes favorisant la prolifération et/ou la différentiation de cellules de testicules, et peuvent aussi être utilisés dans le développement de contraceptifs spécifiques à l'homme et de traitements de la stérilité.

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