Testosterone derivative

Details Testosterone derivative Testosterone derivative

C - Chemistry, Metallurgy

07

J

C07J 1/00 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2333985

The invention is the novel androgen (7.alpha.,17.beta.)-7-methyl-17-[(1- oxoundecyl)oxy]estr-4-en-3-one (MENT undecanoate). This compound distinguishes favourably from other testosterone derivatives in that it has a good solubility in oily media. It particularly exhibits a good dissolved potency relative to testosterone. The compound is particularly suitable for administration by means of injection.

L'invention concerne le nouvel androgène (7 alpha ,17 beta )-7-méthyl-17-[(1-oxo-undécyl)oxy]estr-4-en-3-one (undécanoate de 7 alpha -méthyl-19-nortestostérone -MENT-). Ce composé se distingue favorablement des autres dérivés testostérone en ce qu'il possède une bonne solubilité dans des milieux huileux, et en ce qu'il démontre notamment un bon pouvoir de dissolution par rapport à la testostérone. Ce composé est spécialement conçu pour être administré par injection.

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