Testosterone stabilisation in transdermal devices

Details Testosterone stabilisation in transdermal devices Testosterone stabilisation in transdermal devices

A - Human Necessities

61

J

A61J 1/00 (2006.01) A61K 31/568 (2006.01) B65D 81/26 (2006.01)

Patent

CA 2635422

The invention relates to chemically stabilising testosterone contained in self-adhesive transdermal devices by associating a desiccant agent with the device in a sealed package. The use of said desiccant agent makes it possible to limit the testosterone chemical degradation into androstenedione and other impurities, thereby enabling said device to be preserved during thirty six months.

La présente invention concerne la stabilisation chimique de la testostérone contenue dans des dispositifs transdermiques autoadhésifs via l'association d'un agent dessicant avec ledit dispositif au sein d'un emballage étanche. L'utilisation d'un agent dessicant permet de limiter la dégradation chimique de la testostérone en androstènedione et autres impuretés et assure ainsi une conservation dudit dispositif sur des durées allant jusqu'à trente-six mois.

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