A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
195/139, 260/233
A61K 39/395 (2006.01) C07H 5/02 (2006.01)
Patent
CA 1282728
ABSTRACT The novel chlorinated sugar 0-.alpha.-D-6-chloro-6- deoxygalactopyranosyl-(1?6)-.alpha.-D-4-chloro-4- deoxygalactopyranosyl-(1?2)-.beta.-D-1, 6-dichloro-1, 6-dideoxyfructofuranoside (TCR) can be used to prepare sucralose by incubating the TCR in solution in the presence of an enzyme serving to remove the 6-chloro-6-deoxygalactosyl moiety from the 6-position, especially an enzyme derived from a strain of Mortierella vinacea, Circinella muscae or Aspergillus niger. TCR is prepared by treating raffinose with thionyl chloride in the presence of triphenylphosphine oxide.
520919
Cheetham Peter Samuel James
Dordick Jonathan Seth
Hacking Andrew John
Khan Riaz Ahmed
Mufti Khizar Sultan
Marks & Clerk
Tate & Lyle Public Limited Company
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