Tetracyclic azapyrazinoindolines as 5-ht2 ligands

C - Chemistry – Metallurgy – 07 – D

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C07D 471/22 (2006.01) A61K 31/4985 (2006.01) C07D 491/22 (2006.01) C07D 495/22 (2006.01)

Patent

CA 2609634

The present invention refers to chemical compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1. These compounds can be used for the preparation of medicaments. And wherein C4 and C6 form together with R1 and R2 a further clic part.

La présente invention concerne des composés chimiques représentés par la formule (I), ainsi que des sels et esters acceptables d'un point de vue pharmaceutique de ceux-ci, R1 à R5 étant tels que décrits dans la revendication 1. Ces composés peuvent être utilisés dans la préparation de médicaments. C4 et C6 forment conjointement à R1 et R2 une autre partie de ladite formule.

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