Tetracyclic compounds as dopamine agonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 495/04 (2006.01) A61K 31/47 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2159481

A tetracyclic compound of formula (I) wherein A and the atoms to which it is attached and the optional double bond represent a mono- or di-heterocyclic ring selected from formulas (a), (b), (c), (d) and (e) wherein R1, R2, R3, R4 and X are specifically defined, which compounds are useful in the treatment of dopamino-related neurological, psychological and cardiovascular disorders as well as in the treatment of substance abuse and other addictive behavior disorders, cognitive impairment and attention deficit disorder.

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