Tetracyclic compounds as estrogen ligands

Details Tetracyclic compounds as estrogen ligands Tetracyclic compounds as estrogen ligands

C - Chemistry, Metallurgy

07

D

C07D 307/77 (2006.01) A61K 31/343 (2006.01) A61K 31/352 (2006.01) A61P 3/06 (2006.01) A61P 15/18 (2006.01) A61P 19/10 (2006.01) A61P 25/00 (2006.01) C07D 493/04 (2006.01) C07J 69/00 (2006.01)

Patent

CA 2570518

This invention provides estrogen receptor modulators having the structure: (I) wherein R1, R2, R3, R4, Q, n, R8, R9, R10, and R11 have been defined in the specification; or a pharmaceutically acceptable salt thereof. The invention further provides methods for the preparation and use of the compounds.

L'invention concerne des modulateurs des récepteurs des oestrogènes de structure (I), dans laquelle R1, R2, R3, R4, Q, n, R8, R9, R10, et R11 sont tels que définis dans la description ; ou un sel pharmaceutiquement acceptable desdits modulateurs. L'invention concerne également des méthodes de préparation et d'utilisation desdits composés.

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