Tetracyclic derivatives as spla2 inhibitors

Details Tetracyclic derivatives as spla2 inhibitors Tetracyclic derivatives as spla2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/80 (2006.01) A61K 31/407 (2006.01) A61P 29/00 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2431721

A novel class of tetracyclic compounds of formula (I) is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

L'invention concerne une nouvelle classe de composés tétracycliques, ainsi que l'utilisation de tels composés pour inhiber la libération d'acides gras par la sPLA2 pour le traitement de maladies inflammatoires, telles que le choc septique.

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