C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/14 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2066695
2066695 9103478 PCTABS00003 New imidazoquinazoline compounds having general formula (I), wherein A together with the .alpha.-marked carbon atom and the .beta.-marked nitrogen atom is one of the groups (a, b, c), wherein R4, R5, R6 and R7 independently are hydrogen, halogen C1-6-alkyl, aryl or aralkyl. R1 is (d, e, f, g), cyano or CO2R8, wherein R8 is hydrogen, C1-6-alkyl or C3-7-cycloalkyl, trifluoromethyl or C1-6-alkoxymethyl, R2 and R3 independently are hydrogen, halogen, CN, C1-6-alkyl, C2-6-alkenyl, C2-6-alkynyl, trifluoromethyl, C1-6-alkoxy, dialkylaminoalkoxy, aralkoxy, aryloxy which may be substituted with halogen or alkoxy, a cyclic amino group, or NR9R10, wherein R9 and R10 independently are hydrogen or C1-6-alkyl. The compounds are useful in psychopharmaceutical preparations as anticonvulsants, anxiolytics, hypnotics, antipsychotics, antiemetics, or in improving the cognitive function of the brain of mammals.
Hansen Holger C.
Kristiansen Marit
Mccarthy Tetrault Llp
Novo Nordisk A/s
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