C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/5517 (2006.01) A61K 31/553 (2006.01) A61P 31/00 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2628937
The present invention relates to tetracyclic indole derivatives of formula (I); wherein Ar, D1, D2, D3, D4, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
La présente invention concerne des dérivés tétracycliques d'indole de formule (I), où Ar, D1, D2, D3, D4, W, X, Y et Z sont tels que définis dans la présente, ainsi que des sels de qualité pharmaceutique desdits dérivés, des préparations pharmaceutiques les incluant, et leur application au traitement prophylactique ou thérapeutique d'une infection par le virus de l'hépatite C.
Di Filippo Marcello
Harper Steven
Narjes Frank
Pacini Barbara
Petrocchi Alessia
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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