Tetracyclic inhibitors of fatty acid amide hydrolase

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/04 (2006.01) A61K 31/437 (2006.01) A61K 31/44 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2687941

Certain tetracyclic compounds are described, which may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).

L'invention concerne certains composés tétracycliques, qui peuvent être utilisés dans des compositions pharmaceutiques et des procédés pour traiter des états maladifs, des troubles et des affections véhiculés par une activité de l'hydrolase d'amide d'acide gras (FAAH). Ainsi, les composés peuvent être administrés pour traiter, par exemple, l'anxiété, la douleur, l'inflammation, les troubles du sommeil, les troubles de l'alimentation ou les troubles du mouvement (tels que la sclérose en plaques).

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