Tetracyclic kinase inhibitors

Details Tetracyclic kinase inhibitors Tetracyclic kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/14 (2006.01) A61K 31/4162 (2006.01) A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/55 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2631871

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula (I): I wherein X, Y, Z, R1, R2, R3, Ra, Rb, and n are as described herein.

L'invention concerne de nouveaux inhibiteurs de kinase qui sont utiles en tant qu'agents thérapeutiques, par exemple dans le traitement de tumeurs, les composés répondant à la formule générale (I), dans laquelle X, Y, Z, R1, R2, R3, Ra, Rb et n sont tels que définis dans la description.

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