Tetrahydro-1h-benzazepinones containing acid surrogates

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 223/16 (2006.01) A61K 31/55 (2006.01) C07D 223/12 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 417/12 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2168131

This invention relates to compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the application These com- pounds are CCK-B receptor antagonists and are useful in the treatment and preven- tion of central nervous sys- tem and gastrointestinal dis- orders.

L'invention porte sur des composés de formule (I), où R1, R2, R3, R4 et X ont la signification spécifiée dans la demande. Ces composés sont des antagonistes des récepteurs de la CCK-B et sont utiles pour le traitement et la prévention des troubles gastro-intestinaux et de ceux du SNC.

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