Tetrahydro-2h-benzo¬c|pyrroles

Details Tetrahydro-2h-benzo¬c|pyrroles Tetrahydro-2h-benzo¬c|pyrroles

C - Chemistry, Metallurgy

07

D

260/321

C07D 209/44 (2006.01) C07D 237/30 (2006.01)

Patent

CA 1105473

X-4658A -1- Abstract of the Disclosure Novel tetrahydro-2H-benzo[c]pyrroles, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinson's syndrome, are described herein. These compounds are prepared by reacting a dl-5-amino-4,5,6,7-tetrahydro- 2H-benzo[c]pyrrole with an aldehyde and then a reducing agent or with an alkyl halide, then an acyl halide followed by a reducing agent; and optionally with an alkyl halide and base.

330566

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