C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/276
C07D 471/04 (2006.01)
Patent
CA 1251449
- 1 - Abstract: The invention provides tetrahydro-.beta.-carboline derivatives of the formula: Image (I) wherein R1 is hydrogen atom, a lower alkyl group, a cycloalkyl group, phenyl group or a hydroxy-substituted lower alkyl group, R2 is hydrogen atom, an alkyl group, or a group of the formula: -(CH2)mY, Y is thenyl or a substituted or unsubstituted phenyl group, and m and n are an integer of 1 or 2. These derivatives can alle- viate, prevent or cure hepatic damage and are useful as therapeutic or prophylactic agents for hepatic diseases. A process for the preparation of these compounds is also provided.
455559
Iijima Ikuo
Matsumoto Mamoru
Matsuoka Yuzo
Miyagishima Toshikazu
Saiga Yutaka
Kirby Eades Gale Baker
Tanabe Seiyaku Co. Ltd.
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