C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/276
C07D 471/04 (2006.01) A61K 31/395 (2006.01)
Patent
CA 1269981
ABSTRACT OF THE DISCLOSURE 5,6,7,8-tetrahydro-beta-carbolines derivatives of formula I Image (I) > wherein R1 is an oxadiazolyl radical of the formula Image , COOR3 or CONR4R5, R2 is H, lower alkyl, R3 is H or lower alkyl, R4 and R5 are H or lower alkyl, whereby R4 and R5 cannot be hydrogen at the same time, or R4 and R5 together with the adjacent nitrogen atom form a 5- or 6-member ring, which additionally can contain a heteroatom, and RA is hydrogen, =0, cycloalkyl, -COOR3 with R3 having the above-mentioned meanings, or lower alkyl, which optionally can be substituted by OH, halogen, lower alkoxy, phenyl, phenyloxy, -NR4R5, whereby R4 and R5 have the above-mentioned meanings, and RB can be hydrogen, lower alkyl or lower alkoxyalkyl, have valuable pharmacological properties.
519910
Biere Helmut
Engelstoft Mogens
Huth Andreas
Rahtz Dieter
Schmiechen Ralph
Marks & Clerk
Schering Aktiengesellschaft
LandOfFree
Tetrahydro-.beta.-carbolines, process for their production... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tetrahydro-.beta.-carbolines, process for their production..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydro-.beta.-carbolines, process for their production... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1285718