Tetrahydro-imidazo[1,5-.alpha.]pyrazine derivatives,...

Details Tetrahydro-imidazo[1,5-.alpha.]pyrazine derivatives,... Tetrahydro-imidazo[1,5-.alpha.]pyrazine derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/498 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 5/48 (2006.01)

Patent

CA 2706735

Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitor, wherein the substituents of formula (I) are defined as same as the description. (see formula I)

L'invention porte sur des dérivés de tétrahydroimidazo[1,5-a]pyrazine représentés par la formule I, sur leurs procédés de préparation, sur des compositions pharmaceutiques contenant les dérivés et sur leurs utilisations en tant que médicaments, notamment en tant qu'inhibiteurs de la dipeptidyl peptidase IV, les substituants dans la formule I étant tels que définis dans la description.

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