Tetrahydro-naphthalene and urea derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/62 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61P 13/00 (2006.01) A61P 29/00 (2006.01) C07D 295/215 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2540647

This invention relates to a hydroxy-tetrahydro-naphthalene or an urea derivative formula (I) and salts thereof which are useful as active ingredients of pharmaceutical preparations, wherein A represents formula (II) or (III) wherein # represents the connection position to the molecule and Q1a, Q2a, Q3a and Q4a are defined, and E represents formula (IV) or (V) wherein # represents the connection position to the molecule and Q1b, Q2b, Q3b, Q4b, Q5b, R1b, na, ma, Xa and Ra are defined.

L'invention concerne un hydroxy-tétrahydro-naphtalène ou un dérivé d'urée de formule (I) et des sels de ceux-ci, lesquels sont utiles comme principes actifs de préparations pharmaceutiques, dans laquelle A désigne la formula (II) ou (III), dans laquelle # désigne la position de connexion à la molécule et Q¿1a?, Q¿2a?, Q¿3a? et Q¿4a? sont définis dans la description et E représente la formule (IV) ou (V), dans laquelle # désigne la position de connexion à la molécule et Q¿1b?, Q¿2b?, Q¿3b?, Q¿4b?, Q¿5b?, R?1b¿, na, ma, X¿a ?et R¿a? sont définis dans la description.

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