C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 3/04 (2006.01)
Patent
CA 2438596
The present invention refers to chemical compounds of formula (I) as well as pharmaceutically acceptable salts, solvates and esters thereof, wherein R1 to R7 have the significance given in the description and the claims. The compounds can be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, damage to the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes insipidus, type II diabetes, obesity and sleep apnoea.
La présente invention concerne des composés chimiques de formule (I), ainsi que des sels, des solvates et des esters pharmaceutiquement acceptables de ceux-ci, R?1¿ à R?7¿ possédant les significations spécifiées dans la description et les revendications. Ces composés peuvent être utilisés sous forme de préparations pharmaceutiques en traitement ou prévention de troubles ou affections du système nerveux central, de troubles cardio-vasculaires, de troubles gastro-intestinaux, du diabète insipide, du diabète de type II, de l'obésité et de l'apnée du sommeil.
Hebeisen Paul
Mattei Patrizio
Muller Marc
Richter Hans
Roever Stephan
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
Vernalis Research Limited
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