Tetrahydro-pyrrolizinone compounds as lfa-i mediators

Details Tetrahydro-pyrrolizinone compounds as lfa-i mediators Tetrahydro-pyrrolizinone compounds as lfa-i mediators

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/403 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2624488

Tetrahydro-pyrrolizinone compounds which mediate the activity of LFA-1 with its ligands involved in cell adhesion, migration and activation.

La présente invention concerne des composés de tétrahydro-pyrrolizinone qui assurent la médiation de l'activité de la LFA-1 avec ses ligands mis en jeu dans l'adhérence, la migration et l'activation des cellules.

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