Tetrahydrocorynantheine derivatives and process for their...

Details Tetrahydrocorynantheine derivatives and process for their... Tetrahydrocorynantheine derivatives and process for their...

C - Chemistry, Metallurgy

07

D

167/231, 260/272

C07D 459/00 (2006.01) A61K 31/435 (2006.01) A61K 31/475 (2006.01) C07D 471/14 (2006.01)

Patent

CA 1250582

ABSTRACT The present invention provides corynantheine derivatives of the general formula:- (I) Image wherein R is a hydrogen or alkali metal atom, an ammonium group or the residue of an amine or an alkyl radical containing up to 4 carbon atoms; and the physiologically acceptable acid-addition salts thereof. The present invention also provides processes for the preparation of these corynantheine derivatives and pharmaceutical compositions containing them. Furthermore, the present invention is concerned with the use of dihydrocorynantheine as an antihypertonic.

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