Tetrahydroindole and tetrahydroindazole derivatives

Details Tetrahydroindole and tetrahydroindazole derivatives Tetrahydroindole and tetrahydroindazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/4025 (2006.01) A61K 31/416 (2006.01) A61K 31/4178 (2006.01) A61K 31/4402 (2006.01) A61K 31/445 (2006.01) A61P 29/00 (2006.01) A61P 31/10 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2684240

The invention provides indole and indazole compounds of Formula (I) or pharmaceutically acceptable salts thereof which are useful for treating and/or preventing diseases and/or disorders ameliorated by the inhibition of Heat-Shock Protein 90. The invention further provides pharmaceutical compositions comprising compounds of Formula (I) and methods of preparing compounds of Formula (I).

L'invention concerne des composés d'indole et d'indazole de formule (I) ou leurs sels pharmaceutiquement acceptables. Les composés selon l'invention sont utiles pour le traitement et/ou la prévention de maladies et/ou de troubles améliorés par l'inhibition de la protéine Hsp90 (Heat-Shock Protein 90). L'invention concerne également des compositions pharmaceutiques qui comprennent des composés de formule (I) et des procédés de préparation des composés de formule (I).

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